The NUP43 Polyclonal Antibody (CAB15983) is a valuable tool for researchers studying the nucleoporin NUP43 and its role in cellular processes such as nucleocytoplasmic transport. This antibody, produced in rabbits, exhibits high reactivity with NUP43 in human samples and is suitable for use in Western blot applications. By binding to the NUP43 protein, this antibody allows for the detection and analysis of NUP43 in various cell types, making it an essential resource for investigations in cell biology and molecular biology.NUP43 is a component of the nuclear pore complex, which regulates the transport of molecules between the nucleus and cytoplasm. Dysfunction of NUP43 has been implicated in various diseases, including cancer and neurological disorders, highlighting the importance of studying its function.
By using the NUP43 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying nucleocytoplasmic transport and its implications for human health.Overall, the NUP43 Polyclonal Antibody (CAB15983) is a reliable tool for studying NUP43 in research settings, offering high specificity and sensitivity for Western blot applications. Its use can contribute to advancing our understanding of the role of NUP43 in cellular processes and disease pathology, ultimately paving the way for the development of novel therapeutic strategies.
Product Name:
NUP43 Rabbit Polyclonal Antibody
SKU:
CAB15983
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1).
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).
Purification Method:
Affinity purification
Gene ID:
348995
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NUP43 Rabbit pAb (CAB15983) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
