The NUP35 Polyclonal Antibody (CAB12762) is a valuable tool for researchers studying nucleoporin 35 (NUP35), a key protein involved in nucleocytoplasmic transport. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.NUP35 is a crucial component of the nuclear pore complex, which regulates the transport of molecules between the nucleus and cytoplasm. Dysregulation of nucleocytoplasmic transport has been implicated in various diseases, including cancer, neurodegenerative disorders, and viral infections.
By targeting NUP35, researchers can gain insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.With its high reactivity and specificity, the NUP35 Polyclonal Antibody is an essential tool for studying the role of NUP35 in cellular processes and disease pathology. Whether investigating the molecular mechanisms of nucleocytoplasmic transport or exploring potential therapeutic interventions, this antibody is a valuable asset for researchers in the fields of cell biology, molecular biology, and biomedical research.
Product Name:
NUP35 Rabbit Polyclonal Antibody
SKU:
CAB12762
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human NUP35 (NP_612142.2).
This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10.
Purification Method:
Affinity purification
Gene ID:
129401
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NUP35 Rabbit pAb (CAB12762) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
