Anti-NUP210 Antibody (CAB19895)[KO Validated]
- SKU:
- CAB19895
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Anti-NUP210 Antibody (CAB19895)[KO Validated]
The NUP210 Polyclonal Antibody (CAB19895) is a valuable tool for researchers studying the nuclear pore complex protein NUP210. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for Western blot applications. By binding to the NUP210 protein, researchers can detect and analyze its expression in various cell types, offering insights into its function in cellular processes.NUP210 is a key component of the nuclear pore complex, a critical structure for regulating nucleocytoplasmic transport and gene expression.
Dysregulation of NUP210 has been linked to various diseases, including cancer and neurodegenerative disorders. By studying NUP210 with this antibody, researchers can uncover its role in these diseases and potentially identify new therapeutic targets.Overall, the NUP210 Polyclonal Antibody (CAB19895) provides researchers with a reliable tool for investigating the function of NUP210 in cellular biology and disease pathways. Its high specificity and reactivity make it a valuable asset for studies in molecular biology, cell biology, and disease research.
| Antibody Name: | Anti-NUP210 Antibody [KO Validated] |
| Antibody SKU: | CAB19895 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human NUP210. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T |
| Immunogen: | Recombinant protein of human NUP210. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23225 |
| Uniprot: | Q8TEM1 |
| Cellular Location: | |
| Calculated MW: | 205kDa |
| Observed MW: | 290KDa |
![Anti-NUP210 Antibody [KO Validated] (CAB19895)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/y/427/A19895_1__34404.jpg) | Western blot analysis of extracts from normal (control) and NUP210 knockout (KO) 293T cells, using NUP210 antibody (CAB19895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
| Synonyms: | NUP210, GP210, POM210 |
| Background: | The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. |
| UniProt Protein Function: | NUP210: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Belongs to the NUP210 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleoporin; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: membrane; nuclear envelope; nuclear pore Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription |
| NCBI Summary: | The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q8TEM1 |
| NCBI GenInfo Identifier: | 116242720 |
| NCBI Gene ID: | 23225 |
| NCBI Accession: | Q8TEM1.3 |
| UniProt Secondary Accession: | Q8TEM1,O94980, Q6NXG6, Q8NBJ1, Q9H6C8, Q9UFP3, A6NN56 |
| UniProt Related Accession: | Q8TEM1 |
| Molecular Weight: | 105,810 Da |
| NCBI Full Name: | Nuclear pore membrane glycoprotein 210 |
| NCBI Synonym Full Names: | nucleoporin 210 |
| NCBI Official Symbol: | NUP210Â Â |
| NCBI Official Synonym Symbols: | GP210; POM210Â Â |
| NCBI Protein Information: | nuclear pore membrane glycoprotein 210 |
| UniProt Protein Name: | Nuclear pore membrane glycoprotein 210 |
| UniProt Synonym Protein Names: | Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDa |
| Protein Family: | Nuclear pore membrane glycoprotein |
| UniProt Gene Name: | NUP210Â Â |
| UniProt Entry Name: | PO210_HUMAN |
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