The NUP160 Polyclonal Antibody (CAB13080) is a valuable tool for researchers studying NUP160, a key component of the nuclear pore complex. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the NUP160 protein, researchers can accurately detect and analyze its presence in various cell types.NUP160 plays a crucial role in regulating the transport of macromolecules between the nucleus and cytoplasm, making it essential for fundamental cellular processes such as gene expression and signal transduction.
Dysfunction in NUP160 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic intervention.By understanding the role of NUP160 in cellular function and disease pathology, researchers can uncover new insights into mechanisms underlying these conditions and potentially develop novel treatment strategies. The NUP160 Polyclonal Antibody is a valuable tool for advancing research in molecular biology, cell biology, and disease mechanisms.
Product Name:
NUP160 Rabbit Polyclonal Antibody
SKU:
CAB13080
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human NUP160 (NP_056046.1).
A structural constituent of nuclear pore. Involved in mRNA export from nucleus and nephron development. Part of nuclear pore outer ring. Colocalizes with kinetochore. Implicated in nephrotic syndrome type 19.
Purification Method:
Affinity purification
Gene ID:
23279
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NUP160 Rabbit pAb (CAB13080) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 180s.
