The NUP155 Monoclonal Antibody is a valuable tool for researchers studying the NUP155 protein, a key component of the nuclear pore complex involved in regulating nucleocytoplasmic transport. This antibody, generated through monoclonal antibody technology, is highly specific to human NUP155 and has been validated for use in various applications including immunofluorescence and immunoprecipitation.NUP155 plays a crucial role in the transport of molecules in and out of the nucleus, making it essential for cellular homeostasis and regulation. Dysregulation of NUP155 has been implicated in various diseases including cancer and neurodegenerative disorders, making it a promising target for drug development and therapeutic interventions.
By utilizing the NUP155 Monoclonal Antibody, researchers can accurately detect and study the expression and localization of NUP155 in different cell types and tissues, providing valuable insights into its function and potential implications in disease pathology. This antibody is a valuable tool for advancing research in molecular biology, cell biology, and biomedical sciences.
Product Name:
NUP155 Monoclonal Antibody
SKU:
CAB21138
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 901-1050 of human NUP155 (NP_705618.1).
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
9631
Clone Number:
ARC3030
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using NUP155 Rabbit mAb (CAB21138) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
