NUP133 Rabbit Polyclonal Antibody (CAB8818)
- SKU:
- CAB8818
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | NUP133 Rabbit Polyclonal Antibody |
SKU: | CAB8818 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-930 of human NUP133 (NP_060700.2). |
Sequence: | NILK DMLQ AASH YRQN RNSL YRRE ESLE KEPE YVPW TATS GPGG IRTV IIRQ HEIV LKVA YPQA DSNL RNIV TEQL VALI DCFL DGYV SQLK SVDK SSNR ERYD NLEM EYLQ KRSD LLSP LLSL GQYL WAAS LAEK YCDF DILV QMCE QTDN QSRL QRYM TQFA DQNF SDFL FRWY LEKG KRGK LLSQ PISQ HGQL ANFL Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | GAMOS8; NPHS18; hNUP133; NUP133 |
Positive Sample: | A375,LO2,HeLa,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, centromere, kinetochore, nuclear pore complex. |
Calculated MW: | 129kDa |
Observed MW: | 133kDa |
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.
Purification Method: | Affinity purification |
Gene ID: | 55746 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |