The NUP107 Polyclonal Antibody (CAB13110) is a valuable tool for researchers studying nucleoporin 107 (NUP107), a key component of the nuclear pore complex essential for nucleocytoplasmic transport. This antibody, produced in rabbits, is highly specific for detecting NUP107 in human samples and has been validated for use in Western blot applications. By binding to the NUP107 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and molecular biology.NUP107 is crucial for regulating the transport of macromolecules between the nucleus and cytoplasm, playing a vital role in maintaining cellular homeostasis.
Dysregulation of NUP107 has been implicated in various diseases, including cancer, neurodegenerative disorders, and viral infections. Understanding the function of NUP107 is essential for uncovering its role in these conditions and developing targeted therapies to modulate nucleocytoplasmic transport. Researchers can rely on the NUP107 Polyclonal Antibody to facilitate their studies and advance our knowledge of this critical cellular process.
Product Name:
NUP107 Rabbit Polyclonal Antibody
SKU:
CAB13110
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 766-925 of human NUP107 (NP_065134.1).
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Purification Method:
Affinity purification
Gene ID:
57122
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NUP107 Rabbit pAb (CAB13110) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
