The NUGGC Antibody (PAC062479) is a polyclonal antibody that targets the NUGGC protein, which is involved in regulating immune responses. This antibody is derived from rabbits and has high reactivity with human samples, making it suitable for research purposes. It is validated for use in Western blot applications and enables the detection and analysis of NUGGC in various cell types.NUGGC is a key player in immune regulation and has been implicated in various diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
By studying the role of NUGGC, researchers can gain insights into immune modulation and potentially develop new therapies for these conditions. This antibody is a valuable tool for investigations in immunology and cancer research, providing a deeper understanding of immune response mechanisms.
Antibody Name:
NUGGC Antibody (PACO62479)
Antibody SKU:
PACO62479
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Nuclear GTPase SLIP-GC protein (1-228AA)
Western Blot. Positive WB detected in: HepG2 whole cell lysate, K562 whole cell lysate, SH-SY5Y whole cell lysate, HL-60 whole cell lysate. All lanes: NUGGC antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 92 kDa. Observed band size: 92 kDa.
Background:
Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).
Synonyms:
Nuclear GTPase SLIP-GC (EC 3.6.1) (Speckled-like pattern in the germinal center), NUGGC, C8orf80
UniProt Protein Function:
NUGGC: Plays a role as replication-related GTPase protein in germinal center B-cell.Protein type: EC 3.6.1.-Chromosomal Location of Human Ortholog: 8p21.1
