The NUFIP1 Polyclonal Antibody (PAC010963) is a powerful tool for researchers studying NUFIP1, a protein involved in RNA processing and transport within the cell. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the NUFIP1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and cellular metabolism.
NUFIP1 plays a crucial role in the regulation of RNA metabolism, including the transport of specific mRNAs to ribosomes for protein synthesis. Dysregulation of NUFIP1 has been implicated in various diseases, such as cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. By investigating the function and mechanisms of NUFIP1, researchers can gain valuable insights into disease pathogenesis and potential treatment strategies.
nuclear fragile X mental retardation protein interacting protein 1;NUFIP1;NUFIP;bA540M5.1 ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012]
