The NUDT21 Polyclonal Antibody (CAB4482) is a versatile tool designed for researchers studying NUDT21, a protein involved in mRNA processing and gene expression regulation. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blotting applications. It specifically binds to the NUDT21 protein, enabling accurate detection and analysis in a variety of cell types.NUDT21, also known as CFIm25, plays a crucial role in pre-mRNA 3' end processing and polyadenylation, making it an essential component of gene expression regulation. Its involvement in these processes makes it an intriguing target for studies related to gene regulation, RNA processing, and mRNA stability.
Researchers investigating various cellular processes, such as transcription and RNA metabolism, can benefit from using this antibody in their experiments.By understanding the function and localization of NUDT21 in cells, researchers can gain valuable insights into its role in gene expression regulation and potentially uncover new therapeutic targets for diseases related to RNA processing dysregulation. The NUDT21 Polyclonal Antibody is a valuable tool for advancing research in molecular biology, genetics, and related fields.
Product Name:
NUDT21 Rabbit Polyclonal Antibody
SKU:
CAB4482
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human NUDT21 (NP_008937.1).
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.
Purification Method:
Affinity purification
Gene ID:
11051
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NUDT21 Rabbit pAb (CAB4482) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
