The NUDT2 Polyclonal Antibody (CAB6868) is a vital tool for researchers studying NUDT2, a protein involved in nucleotide metabolism and stress responses. This antibody, developed in rabbits, demonstrates high reactivity towards human samples and is suitable for use in Western blotting applications. By binding specifically to the NUDT2 protein, this antibody allows for reliable detection and analysis in a variety of cell types, making it an excellent choice for investigations in biochemistry and molecular biology.NUDT2, also known as nudix hydrolase 2, plays a crucial role in maintaining cellular nucleotide pool balance and protecting cells from oxidative stress.
Its functions are essential for proper cell function and survival, making it a promising target for research in cancer biology, neurodegenerative disorders, and metabolic diseases. Understanding the mechanisms by which NUDT2 operates is fundamental for developing therapies that target nucleotide metabolism pathways and combat related diseases.Whether you are delving into the intricacies of nucleotide metabolism or exploring stress response pathways, the NUDT2 Polyclonal Antibody (CAB6868) is a valuable tool that can enhance your research endeavors and contribute to the advancement of scientific knowledge in these fields.
Product Name:
NUDT2 Rabbit Polyclonal Antibody
SKU:
CAB6868
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human NUDT2 (NP_001152.1).
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
318
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NUDT2 antibody (CAB6868) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
