The NUDT18 Polyclonal Antibody (CAB8514) is specifically designed for research involving NUDT18, a nucleoside diphosphate-linked moiety X motif 18 protein involved in nucleotide metabolism. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.NUDT18 plays a crucial role in maintaining genome stability by regulating nucleotide metabolism and DNA repair processes. Dysregulation of NUDT18 has been implicated in various diseases including cancer, neurodegenerative disorders, and metabolic diseases.
By targeting NUDT18, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets.The NUDT18 Polyclonal Antibody enables precise detection and analysis of NUDT18 protein levels in different cell types, making it a valuable tool for studies in molecular biology, biochemistry, and biotechnology. By understanding the role of NUDT18 in cellular processes, researchers can further advance their knowledge of disease mechanisms and develop targeted interventions for improved patient outcomes.
Product Name:
NUDT18 Rabbit Polyclonal Antibody
SKU:
CAB8514
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human NUDT18 (NP_079091.3).
The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates.
Purification Method:
Affinity purification
Gene ID:
79873
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of MCF-7 cells, using NUDT18 antibody (CAB8514) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
