The NUDEL Rabbit Monoclonal Antibody (CAB3799) is a powerful research tool designed for studies involving NUDEL, a key protein involved in neuronal development and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting NUDEL in various experimental settings.With its exceptional reactivity towards human samples, the NUDEL Rabbit Monoclonal Antibody is ideal for use in Western blot applications, immunofluorescence, and immunohistochemistry. Its ability to bind specifically to the NUDEL protein allows for accurate detection and analysis in neuronal cell types, making it an invaluable tool for neuroscience and neurobiology research.
NUDEL is essential for microtubule organization and plays a crucial role in neuronal migration and axonal growth. Dysregulation of NUDEL function has been associated with neurodevelopmental disorders and neurological diseases. Therefore, studying the expression and function of NUDEL using this antibody can provide valuable insights into the mechanisms underlying these conditions, potentially leading to the development of novel therapeutic strategies.
Product Name:
NUDEL/NDEL1 Rabbit Monoclonal Antibody
SKU:
CAB3799
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NUDEL/NDEL1 (Q9GZM8).
Chromosome, Cytoplasm, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle.
Calculated MW:
38kDa
Observed MW:
40kDa
Enables identical protein binding activity. Involved in chromosome segregation; positive regulation of GTPase activity; and regulation of intracellular protein transport. Located in kinetochore. Biomarker of schizophrenia.
Purification Method:
Affinity purification
Gene ID:
81565
Clone Number:
ARC0835
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NUDEL/NDEL1 Rabbit mAb (CAB3799) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
