The NUCB2 Polyclonal Antibody (PACO64347) is a valuable tool for researchers studying NUCB2, a protein involved in regulating calcium and insulin secretion in the pancreas. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NUCB2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in endocrinology and metabolic disorders.NUCB2, also known as nucleobindin-2, is a key player in the regulation of calcium levels and insulin secretion, making it a promising target for research in diabetes and related metabolic conditions.
By understanding the function of NUCB2, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic strategies for their treatment. The NUCB2 Polyclonal Antibody is a valuable tool for exploring the role of NUCB2 in health and disease, offering researchers a powerful means of investigating its functions in various cellular contexts.
Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: Nucb2 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 51 kDa. Observed band size: 51 kDa.
Background:
Calcium-binding protein. May have a role in calcium homeostasis (By similarity). {ECO:0000250}.; Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Synonyms:
Nucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into: Nesfatin-1], Nucb2, Nefa
UniProt Protein Function:
Calcium-binding protein. May have a role in calcium homeostasis.
NCBI Summary:
a medial Golgi cisternae resident protein [RGD, Feb 2006]
