The NTSR1 Polyclonal Antibody (CAB3054) is a valuable tool for researchers studying the neurotensin receptor 1 (NTSR1) protein. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the NTSR1 protein, this antibody allows for the detection and analysis of NTSR1 in various cell types, making it ideal for investigations in neuroscience, endocrinology, and pharmacology.NTSR1 is a G protein-coupled receptor that plays a crucial role in mediating the actions of neurotensin, a neuropeptide involved in a wide range of physiological processes.
Dysregulation of NTSR1 signaling has been implicated in various diseases, including schizophrenia, Parkinson's disease, and cancer. Therefore, understanding the functions and regulation of NTSR1 is essential for the development of targeted therapies and treatments for these conditions.Overall, the NTSR1 Polyclonal Antibody (CAB3054) provides researchers with a reliable tool for studying NTSR1 in both normal physiological processes and disease states, contributing to advancements in the field of biomedical research.
Product Name:
NTSR1 Rabbit Polyclonal Antibody
SKU:
CAB3054
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NTSR1 (NP_002522.2).
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.
Purification Method:
Affinity purification
Gene ID:
4923
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from DU145 cells, using NTSR1 Rabbit pAb (CAB3054) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.