The NTS Polyclonal Antibody (CAB12326) is a valuable tool for researchers studying the neurotensin receptor NTS, a G protein-coupled receptor (GPCR) involved in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NTS protein, this antibody allows for the detection and analysis of NTS expression in different cell types, making it ideal for studies in neuroscience and neuropharmacology.The NTS receptor is known to play a crucial role in the regulation of numerous functions, including neurotransmission, pain perception, and cardiovascular function.
Dysregulation of the NTS receptor has been implicated in various neurological and psychiatric disorders, making it a promising target for drug development and therapeutic interventions. By studying the expression and activity of NTS using the CAB12326 Antibody, researchers can gain valuable insights into the role of this receptor in health and disease, paving the way for new treatment strategies.
Product Name:
NTS Rabbit Polyclonal Antibody
SKU:
CAB12326
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-148 of human NTS (NP_006174.1).
This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
Purification Method:
Affinity purification
Gene ID:
4922
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NTS Rabbit pAb (CAB12326) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
