The NTN4 Polyclonal Antibody (CAB13775) is a valuable tool for researchers studying NTN4, a protein involved in cell adhesion and migration processes. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blotting applications. By binding specifically to NTN4, this antibody enables precise detection and analysis of the protein in various cell types, making it an excellent choice for studies in cell biology and cancer research.NTN4, also known as Netrin-4, plays a crucial role in guiding axon growth and cell migration during development.
Its involvement in promoting cell adhesion and influencing cell movement makes it a key player in processes such as angiogenesis and tissue regeneration. Research on NTN4 is essential for gaining insights into its functions and potential therapeutic applications in various diseases, including cancer and neurological disorders.By utilizing the NTN4 Polyclonal Antibody, researchers can delve deeper into the mechanisms through which NTN4 impacts cellular processes, paving the way for the development of novel approaches for targeting NTN4-related pathways in disease treatment and regenerative medicine.
Product Name:
NTN4 Rabbit Polyclonal Antibody
SKU:
CAB13775
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-520 of human NTN4 (NP_067052.2).
This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
59277
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NTN4 Rabbit pAb (CAB13775) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.