The NTN1 Polyclonal Antibody (CAB16236) is a valuable tool for researchers studying the role of NTN1, a protein involved in cell guidance, axon guidance, and angiogenesis. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.NTN1, also known as Netrin-1, is crucial for directing cell migration and axon growth during development and tissue regeneration. Its involvement in angiogenesis makes it a promising target for research in vascular biology and cancer progression. The NTN1 Polyclonal Antibody enables detection and analysis of NTN1 protein expression in different cell types, providing insights into its functions and potential therapeutic applications in conditions like nerve injury, cardiovascular diseases, and cancer metastasis.
Researchers interested in unraveling the molecular mechanisms of cell guidance and vascular development will find the NTN1 Polyclonal Antibody a valuable asset in their studies. Its specificity and sensitivity make it an indispensable tool for investigating the intricate processes regulated by NTN1 in both physiological and pathological contexts.
Product Name:
NTN1 Rabbit Polyclonal Antibody
SKU:
CAB16236
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human NTN1 (NP_004813.2).
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development.
Purification Method:
Affinity purification
Gene ID:
9423
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NTN1 antibody (CAB16236) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.