The NTMT1 Polyclonal Antibody (CAB7098) is a valuable tool for research involving NTMT1, a key enzyme involved in protein methylation. This antibody, produced in rabbits, is highly specific to human NTMT1 and has been validated for use in Western blot applications. By targeting the NTMT1 protein, researchers can study the role of methylation in cellular processes such as gene expression, signaling pathways, and protein function.NTMT1 plays a vital role in regulating the methylation of proteins, which in turn impacts various cellular processes, including DNA repair, cell cycle regulation, and gene transcription. Dysregulation of protein methylation has been implicated in diseases such as cancer, neurological disorders, and developmental abnormalities.
Therefore, studying the function of NTMT1 using this antibody can provide valuable insights into disease mechanisms and potential therapeutic targets.Overall, the NTMT1 Polyclonal Antibody is a versatile tool for investigators interested in unraveling the complex mechanisms of protein methylation and its impact on cellular function and disease pathology. Its high specificity and reliability make it an essential reagent for studies in biochemistry, molecular biology, and drug discovery.
Product Name:
NTMT1 Rabbit Polyclonal Antibody
SKU:
CAB7098
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human NTMT1 (NP_054783.2).
The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).
Purification Method:
Affinity purification
Gene ID:
28989
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NTMT1 antibody (CAB7098) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
