The NTH1 Monoclonal Antibody is a valuable tool for researchers studying NTH1, a key enzyme involved in base excision repair and maintenance of genome stability. This antibody, produced in a monoclonal format, specifically targets the NTH1 protein in various biological samples and is validated for use in immunohistochemistry and immunofluorescence applications.NTH1 is essential for repairing oxidative DNA damage and preventing mutations that can lead to diseases such as cancer.
Its role in DNA repair pathways makes it a promising target for therapeutics aimed at enhancing genome stability and preventing genomic instability-related diseases. The NTH1 Monoclonal Antibody enables researchers to study the function and localization of NTH1 in different cell types, providing insights into its mechanisms of action and potential therapeutic applications in the field of cancer research and DNA damage repair studies.
Product Name:
NTH1 Monoclonal Antibody
SKU:
CAB21118
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human NTH1 (NP_002519.1).
The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
Purification Method:
Affinity purification
Gene ID:
4913
Clone Number:
ARC2991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NTH1 Rabbit mAb (CAB21118) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
