The Neurotrophin-4 Polyclonal Antibody (CAB1081) is a valuable tool for researchers studying neurotrophin-4, a protein that belongs to the neurotrophin family and plays a crucial role in the development and function of the nervous system. This antibody is produced in rabbits and has been validated for use in various applications, including Western blot and immunohistochemistry.Neurotrophin-4 is known for its neurotrophic and neuroprotective properties, making it a key player in neuronal survival, differentiation, and synaptic plasticity. By targeting neurotrophin-4 with this antibody, researchers can study its expression and localization in different cell types and tissues, shedding light on its role in neurodevelopment, neurodegenerative disorders, and neurological diseases.
With its high reactivity and specificity for human samples, the Neurotrophin-4 Polyclonal Antibody (CAB1081) is a reliable tool for investigating the functions and mechanisms of neurotrophin-4 in both normal and pathological conditions. Its applications in neuroscience and neurobiology make it an essential reagent for researchers aiming to unravel the complexities of the nervous system and develop targeted therapies for neurologic disorders.
Product Name:
NTF4 Rabbit Polyclonal Antibody
SKU:
CAB1081
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-210 of human NTF4 (NP_006170.1).
Sequence:
QPPP STLP PFLA PEWD LLSP RVVL SRGA PAGP PLLF LLEA GAFR ESAG APAN RSRR GVSE TAPA SRRG ELAV CDAV SGWV TDRR TAVD LRGR EVEV LGEV PAAG GSPL RQYF FETR CKAD NAEE GGPG AGGG GCRG VDRR HWVS ECKA KQSY VRAL TADA QGRV GWRW IRID TACV CTLL SRTG RA
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
Purification Method:
Affinity purification
Gene ID:
4909
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NTF4 Rabbit pAb (CAB1081) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
