NTAN1 Rabbit Polyclonal Antibody (CAB15562)
- SKU:
- CAB15562
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NTAN1 Rabbit Polyclonal Antibody |
SKU: | CAB15562 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human NTAN1 (NP_775745.1). |
Sequence: | MPLL VEGR RVRL PQSA GDLV RAHP PLEE RARL LRGQ SVQQ VGPQ GLLY VQQR ELAV TSPK DGSI SILG SDDA TTCH IVVL RHTG NGAT CLTH CDGT DTKA EVPL IMNS IKSF SDHA QCGR LEVH LVGG FSDD RQLS QKLT HQLL SEFD RQED DIHL VTLC VTEL NDRE ENEN HFPV IYGI AVNI KTAE IYRA SFQD RGPE EQLR AART LAGG PMIS IYDA ETEQ LRIG PYSW TPFP HVDF WLHQ DDKQ ILEN LSTS PLAE PPHF VEHI RSTL MFLK KHPS PAHT LFSG NKAL LYKK NEDG LWEK ISSP GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | PNAA; PNAD; NTAN1 |
Positive Sample: | 293T,Raji,HepG2,MCF-7,Mouse spleen,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 35kDa |
Observed MW: | 35kDa |
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method: | Affinity purification |
Gene ID: | 123803 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |