The NT5E Polyclonal Antibody (CAB16936) is a valuable tool for research involving the NT5E protein, a cell surface enzyme involved in immune regulation and inflammation. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding specifically to the NT5E protein, this antibody enables the detection and analysis of NT5E in various cell types, making it ideal for studies in immunology and cancer research.
NT5E, also known as CD73, plays a critical role in immune response modulation by regulating inflammation and adenosine signaling. Its involvement in various diseases, including cancer, autoimmune disorders, and inflammatory conditions, makes it a promising target for therapeutic interventions. Understanding the function of NT5E is essential for developing new treatments that can modulate immune responses and potentially improve patient outcomes in these disease contexts.
Product Name:
NT5E Rabbit Polyclonal Antibody
SKU:
CAB16936
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-264 of human CD73/NT5E (NP_002517.1).
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4907
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD73/NT5E Rabbit pAb (CAB16936) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
