| UniProt Protein Function: | NT5C1A: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. Belongs to the 5'-nucleotidase type 3 family.Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Phosphatase (non-protein)Chromosomal Location of Human Ortholog: 1p34.3-p33Cellular Component: cytosolMolecular Function: 5'-nucleotidase activity; magnesium ion binding; nucleotide bindingBiological Process: adenosine metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; nucleoside metabolic process; purine base metabolic process; purine nucleoside monophosphate catabolic process; purine nucleotide catabolic process; pyrimidine base metabolic process; pyrimidine nucleoside catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9BXI3 |
| NCBI GenInfo Identifier: | 47116736 |
| NCBI Gene ID: | 84618 |
| NCBI Accession: | Q9BXI3.1 |
| UniProt Secondary Accession: | Q9BXI3,Q3SYB9, Q5TG98, Q9BWT8 |
| UniProt Related Accession: | Q9BXI3 |
| Molecular Weight: | |
| NCBI Full Name: | Cytosolic 5'-nucleotidase 1A |
| NCBI Synonym Full Names: | 5'-nucleotidase, cytosolic IA |
| NCBI Official Symbol: | NT5C1AÂ Â |
| NCBI Official Synonym Symbols: | CN1; CNI; CN-I; CN1A; CN-IAÂ Â |
| NCBI Protein Information: | cytosolic 5'-nucleotidase 1A |
| UniProt Protein Name: | Cytosolic 5'-nucleotidase 1A |
| UniProt Synonym Protein Names: | Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
| Protein Family: | Cytosolic 5'-nucleotidase |
| UniProt Gene Name: | NT5C1AÂ Â |
| UniProt Entry Name: | 5NT1A_HUMAN |
