The NSUN5 Polyclonal Antibody (CAB5992) is a valuable tool for studying NSUN5, a protein involved in RNA modification and gene regulation. This rabbit-derived antibody is highly specific to human NSUN5 and has been validated for use in applications such as Western blotting. By binding to the NSUN5 protein, this antibody enables researchers to detect and analyze NSUN5 expression in a variety of cell types, making it an ideal choice for studies in molecular biology and RNA biology.NSUN5 is known to play a key role in regulating RNA modification processes, which are essential for ensuring proper gene expression and cellular function. Dysregulation of NSUN5 has been linked to various diseases, including cancer, neurological disorders, and developmental abnormalities.
By investigating the function of NSUN5, researchers can gain insights into the underlying mechanisms of these conditions and potentially identify new therapeutic targets for treatment.Overall, the NSUN5 Polyclonal Antibody is a valuable tool for researchers studying RNA modification and gene regulation, with potential applications in a wide range of biological and medical research areas. Its high specificity and sensitivity make it an essential reagent for gaining a deeper understanding of NSUN5 biology and its implications for human health.
Product Name:
NSUN5 Rabbit Polyclonal Antibody
SKU:
CAB5992
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 127-429 of human NSUN5 (NP_060514.1).
This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
55695
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using NSUN5 Rabbit pAb (CAB5992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
