The NSMCE1 Polyclonal Antibody (CAB15966) offered by AssayGenie is a valuable tool for researchers studying NSMCE1, a key player in DNA repair and chromosome stability. This polyclonal antibody, developed in rabbits, exhibits high specificity for human NSMCE1 samples and has been validated for use in Western blot applications.NSMCE1, also known as Non-SMC Element 1, is involved in the maintenance of genome integrity by promoting the faithful repair of DNA damage and ensuring proper chromosome segregation during cell division. Dysregulation of NSMCE1 has been linked to various genetic disorders and cancers, highlighting its importance in cellular homeostasis.
By utilizing the NSMCE1 Polyclonal Antibody, researchers can accurately detect and analyze NSMCE1 protein levels in different cell types, allowing for a deeper understanding of its role in DNA repair mechanisms and chromosome stability. This antibody is a valuable tool for studies in genetics, cancer biology, and genomic instability, providing new insights into the molecular mechanisms underlying disease development and progression.
Product Name:
NSMCE1 Rabbit Polyclonal Antibody
SKU:
CAB15966
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 7-266 of human NSMCE1 (NP_659547.2).
Enables protein dimerization activity and ubiquitin protein ligase activity. Involved in positive regulation of response to DNA damage stimulus. Located in nucleoplasm. Part of Smc5-Smc6 complex.
Purification Method:
Affinity purification
Gene ID:
197370
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NSMCE1 Rabbit pAb (CAB15966) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
