The NSL1 Polyclonal Antibody (CAB7089) is a versatile tool for researchers studying NSL1, a key protein involved in cell cycle regulation and DNA replication. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting and immunofluorescence.NSL1 is essential for proper chromosome segregation during cell division and is known to interact with other important proteins involved in cell cycle progression. By targeting NSL1 with this antibody, researchers can confidently detect and analyze the protein in a variety of cell types, providing valuable insights into processes like mitosis and DNA replication.
The importance of NSL1 in maintaining genomic stability and preventing abnormal cell growth makes it a compelling target for cancer research and understanding developmental disorders. By studying the role of NSL1 in these contexts, scientists can uncover new therapeutic strategies and potential drug targets for diseases characterized by uncontrolled cell proliferation.
Product Name:
NSL1 Rabbit Polyclonal Antibody
SKU:
CAB7089
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human NSL1 (NP_056286.3).
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.
Purification Method:
Affinity purification
Gene ID:
25936
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of A549 cells using NSL1 antibody (CAB7089).
