The NSG2 Polyclonal Antibody (PAC022470) is a valuable tool for researchers studying NSG2, a protein involved in various cellular processes such as DNA repair and cell maintenance. This antibody is produced in rabbits and has been shown to have high reactivity with human samples, making it suitable for use in Western blot applications. By binding to the NSG2 protein, researchers can detect and analyze its expression in different cell types, making it an ideal choice for studies in cell biology and cancer research.
NSG2, also known as N-methylpurine DNA glycosylase 2, is known to play a crucial role in maintaining genomic stability by repairing DNA damage caused by alkylating agents. Dysregulation of NSG2 has been implicated in cancer development and progression, making it a promising target for further research in oncology. Understanding the function of NSG2 is essential for developing targeted therapies that aim to exploit its role in DNA repair mechanisms in cancer cells.
Antibody Name:
NSG2 Antibody (PACO22470)
Antibody SKU:
PACO22470
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human NSG2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human brain tissue using NSG2 antibody.
Background:
Belongs to the NSG family.
Synonyms:
Neuron-specific protein family member 2; Protein p19; HMP19;
UniProt Protein Function:
NSG2: Belongs to the NSG family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 5q35.2Cellular Component: cytoplasmic vesicle membrane; integral to membraneMolecular Function: clathrin light chain bindingBiological Process: clathrin cage assembly; dopamine receptor signaling pathway
