The NSFL1 cofactor p47 Polyclonal Antibody (CAB6677) is a valuable tool for researchers studying NSFL1 cofactor p47, a protein involved in protein degradation processes within cells. This antibody, produced through immunization of rabbits, exhibits high reactivity with human samples, making it a reliable option for Western blot applications. By binding specifically to NSFL1 cofactor p47, researchers can detect and analyze this protein in a variety of cell types, providing insights into its role in cellular function and potential implications in diseases such as cancer and neurodegenerative disorders.
NSFL1 cofactor p47, also known as UBX domain-containing protein 7, is a crucial component of the ubiquitin proteasome system, which is responsible for degrading unwanted or damaged proteins. Dysregulation of this system has been implicated in various diseases, making NSFL1 cofactor p47 a promising target for research aimed at understanding and potentially treating these conditions. By using the NSFL1 cofactor p47 Polyclonal Antibody, researchers can further investigate the mechanisms underlying protein degradation and its impact on cellular health.
Product Name:
NSFL1C Rabbit Polyclonal Antibody
SKU:
CAB6677
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human NSFL1C (NP_057227.2).
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
Purification Method:
Affinity purification
Gene ID:
55968
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NSFL1C Rabbit pAb (CAB6677) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
