The NSF Polyclonal Antibody (CAB0926) is a valuable tool for researchers studying the NSF protein, which is involved in intracellular membrane fusion events. This antibody, derived from rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding to the NSF protein, it allows for the detection and analysis of this crucial molecule in a variety of cell types.NSF, or N-ethylmaleimide-sensitive factor, plays a vital role in the process of membrane fusion within cells, particularly in the context of vesicle trafficking and exocytosis. Dysregulation of NSF has been implicated in various diseases, including neurodegenerative disorders and viral infections.
By studying the function and regulation of NSF, researchers can gain insights into these pathological processes and potentially identify novel therapeutic targets.The NSF Polyclonal Antibody is a valuable tool for investigating the role of NSF in cellular function and disease pathogenesis. Its high specificity and sensitivity make it well-suited for use in research areas such as cell biology, molecular biology, and neurobiology. By utilizing this antibody, researchers can further our understanding of the intricate mechanisms underlying membrane fusion events and their implications for human health.
Product Name:
NSF Rabbit Polyclonal Antibody
SKU:
CAB0926
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 251-400 of human NSF (NP_006169.2).
Enables PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in intracellular protein transport; positive regulation of protein catabolic process; and positive regulation of receptor recycling. Located in Golgi apparatus; cytosol; and plasma membrane. Implicated in developmental and epileptic encephalopathy.
Purification Method:
Affinity purification
Gene ID:
4905
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NSF Rabbit pAb (CAB0926) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
