The NSF Antibody (PACO33596) is a high-quality polyclonal antibody designed for research involving the N-ethylmaleimide-sensitive factor (NSF). NSF is a key protein involved in membrane fusion, particularly in intracellular vesicle trafficking and neurotransmitter release processes. This rabbit-raised antibody is highly specific to human samples and has been validated for use in Western blot applications.With its ability to target the NSF protein, this antibody allows for precise detection and analysis of NSF in various cell types. This makes it an essential tool for studies in cell biology, neuroscience, and molecular biology.
By understanding the role of NSF in cellular processes, researchers can gain insights into mechanisms underlying diseases such as neurodegenerative disorders, viral infections, and cancer.Overall, the NSF Antibody (PACO33596) provides researchers with a reliable tool to investigate NSF function and its implications in health and disease. Its specificity, sensitivity, and versatility make it a valuable asset for studies aiming to uncover the complex functions of NSF in cellular physiology.
Antibody Name:
Nsf Antibody (PACO33596)
Antibody SKU:
PACO33596
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Vesicle-fusing ATPase protein (7-209AA)
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.
UniProt Protein Details:
NCBI Summary:
binds AMPA receptor GluR2 subunit and acts to disrupt GluR2-PICK1 interactions; may play a role in AMPA receptor trafficking and stabilization [RGD, Feb 2006]
