NRL Transcription Factor Activity Assay
- SKU:
- TFAB00208
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- NRL
- Reactivity:
- Human
- Mouse
Description
NRL Transcription Factor Activity Assay
The NRL Transcription Factor Activity Assay is a cutting-edge kit designed for researchers to accurately measure the activity of NRL transcription factor in cell samples. This assay offers high sensitivity and specificity, allowing for reliable and reproducible results in a wide range of research applications.The NRL transcription factor plays a crucial role in regulating gene expression and is involved in various cellular processes, making it a key target for studying diseases such as retinal degeneration and other ocular diseases.
By measuring NRL transcription factor activity, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and develop potential therapeutic strategies.With its user-friendly protocol and robust performance, the NRL Transcription Factor Activity Assay is an essential tool for researchers looking to advance their understanding of gene regulation and its implications in disease pathology. Trust Assay Genie to provide you with the innovative tools you need for groundbreaking research.
| Product Name: | NRL Transcription Factor Activity Assay |
| Product Code: | TFAB00208 |
| Target: | NRL |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie NRL transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001). |
| NCBI Summary: | This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P54845 |
| NCBI GenInfo Identifier: | 5453802 |
| NCBI Gene ID: | 4901 |
| NCBI Accession: | NP_006168.1 |
| UniProt Secondary Accession: | P54845,Q53XD0, A8MX14, |
| UniProt Related Accession: | P54845 |
| Molecular Weight: | 11,276 Da |
| NCBI Full Name: | neural retina-specific leucine zipper protein isoform 1 |
| NCBI Synonym Full Names: | neural retina leucine zipper |
| NCBI Official Symbol: | NRLÂ Â |
| NCBI Official Synonym Symbols: | RP27; D14S46E; NRL-MAFÂ Â |
| NCBI Protein Information: | neural retina-specific leucine zipper protein |
| UniProt Protein Name: | Neural retina-specific leucine zipper protein |
| Protein Family: | Neural retina-specific leucine zipper protein |
| UniProt Gene Name: | NRLÂ Â |
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