The NRDB Polyclonal Antibody (PACO34012) is a valuable tool for researchers studying the NRDB protein, a key player in DNA repair and replication processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to NRDB, researchers can accurately detect and analyze this crucial protein in various cell types, making it an excellent choice for studies in molecular biology and cancer research.NRDB, also known as DNA repair protein, plays a crucial role in maintaining genomic stability by repairing DNA damage and ensuring accurate replication of genetic material.
Dysregulation of NRDB has been linked to various diseases, including cancer and genetic disorders. Consequently, studying the function of NRDB is essential for developing targeted treatments and therapies for these conditions.Overall, the NRDB Polyclonal Antibody (PACO34012) is a reliable tool for researchers investigating the role of NRDB in DNA repair mechanisms and its implications for disease development. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of genetic stability and potential therapeutic strategies in the field of molecular biology and oncology.
Antibody Name:
nrdB Antibody (PACO34012)
Antibody SKU:
PACO34012
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Ribonucleoside-diphosphate reductase 1 subunit β protein (2-376AA)
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
UniProt Protein Details:
NCBI Summary:
Reducing equivalents provided by glutaredoxin or thioredoxin. [More information is available at EcoGene: EG10661]. The B2 protein of ribonucleoside-diphosphate reductase contains the tyrosyl radical-dinuclear iron center, which is thought to initiate catalysis by long-range electron transfer. [More information is available at EcoCyc: EG10661].
