The NRAP Polyclonal Antibody (CAB12813) is a valuable tool for researchers studying NRAP (Nebulin-related anchoring protein), a protein involved in the organization of myofibrils in muscle cells. This antibody, produced in rabbits, is specifically reactive with human samples and is validated for use in Western blot applications. By binding to NRAP, this antibody allows for the detection and analysis of NRAP in various cell types, making it ideal for studies in muscle development and function.
NRAP is essential for the proper assembly and alignment of sarcomeres within muscle cells, contributing to muscle contraction and overall muscle function. Research into NRAP can provide insights into muscle development, muscle diseases, and potential therapeutic targets for muscular disorders. The NRAP Polyclonal Antibody is a reliable tool for investigating the role of NRAP in muscle biology and can aid in advancing knowledge in the field of muscle research.
Product Name:
NRAP Rabbit Polyclonal Antibody
SKU:
CAB12813
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NRAP (NP_001248392.1).
Predicted to enable actin filament binding activity and muscle alpha-actinin binding activity. Predicted to be involved in cardiac muscle thin filament assembly. Predicted to be located in fascia adherens; muscle tendon junction; and myofibril. Predicted to be active in Z disc.
Purification Method:
Affinity purification
Gene ID:
4892
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using NRAP Rabbit pAb (CAB12813) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
