The NR5A2 Polyclonal Antibody (CAB16854) is a valuable tool for researchers studying the NR5A2 protein, a key transcription factor involved in various biological processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications.NR5A2, also known as steroidogenic factor 1 (SF-1), plays a critical role in regulating genes involved in steroidogenesis, sex differentiation, and embryonic development. Dysregulation of NR5A2 has been implicated in diseases such as adrenal insufficiency, gonadal dysgenesis, and certain types of cancer, making it a promising therapeutic target.
By using the NR5A2 Polyclonal Antibody, researchers can effectively detect and analyze NR5A2 expression in different cell types, aiding in the understanding of its functions and potential implications in various disease states. This antibody is a valuable tool for studies in molecular biology, endocrinology, and cancer research, providing valuable insights into the role of NR5A2 in health and disease.
Product Name:
NR5A2 Rabbit Polyclonal Antibody
SKU:
CAB16854
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human NR5A2 (NP_995582.1).
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development.
Purification Method:
Affinity purification
Gene ID:
2494
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using NR5A2 Rabbit pAb (CAB16854) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
