The NR5A2 Polyclonal Antibody (CAB5766) is a valuable tool for researchers studying NR5A2, a transcription factor involved in various biological processes such as cell differentiation, metabolism, and development. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications. By specifically binding to NR5A2 protein, researchers can accurately detect and analyze its presence in different cell types, making it an essential reagent for studies in molecular biology and genetic regulation.
NR5A2, also known as liver receptor homolog-1 (LRH-1), plays a crucial role in regulating genes involved in cholesterol and bile acid metabolism, as well as glucose homeostasis. Its involvement in these biological pathways makes it a promising target for research on metabolic disorders, liver diseases, and endocrine disorders. Understanding the function of NR5A2 is essential for developing novel therapeutic strategies to target these conditions and uncovering its role in cellular processes and disease progression.
Product Name:
NR5A2 Rabbit Polyclonal Antibody
SKU:
CAB5766
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-541 of human NR5A2 (NP_995582.1).
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development.
Purification Method:
Affinity purification
Gene ID:
2494
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NR5A2 Rabbit pAb (CAB5766) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
