The NR5A2 Polyclonal Antibody (CAB13688) is a potent tool for researchers studying NR5A2, a nuclear receptor protein involved in regulating gene expression and development. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds to NR5A2 with high affinity, allowing for precise detection and analysis in a variety of cell types, making it ideal for studies in developmental biology, endocrinology, and metabolism research.NR5A2, also known as Liver Receptor Homolog-1 (LRH-1), plays a key role in controlling pathways related to metabolism, steroidogenesis, and cell differentiation.
Its importance in these processes makes it a valuable target for investigation in disorders such as diabetes, obesity, and hormone-related cancers. Understanding the function of NR5A2 is essential for developing therapies that can manipulate these pathways for therapeutic benefit.Overall, the NR5A2 Polyclonal Antibody (CAB13688) is a reliable tool for researchers looking to delve into the intricacies of NR5A2 biology and its implications in various disease states. Its specificity and sensitivity make it an essential component in unraveling the complexities of gene regulation and developmental processes.
Product Name:
NR5A2 Rabbit Polyclonal Antibody
SKU:
CAB13688
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-541 of human NR5A2 (NP_995582.1).
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development.
Purification Method:
Affinity purification
Gene ID:
2494
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NR5A2 Rabbit pAb (CAB13688) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
