The NR5A1 Polyclonal Antibody (CAB1657) is a valuable tool for researchers studying NR5A1, a nuclear receptor protein involved in various biological processes, including development, differentiation, and metabolism. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.NR5A1, also known as steroidogenic factor 1 (SF-1), plays a crucial role in regulating genes involved in steroidogenesis and sexual development. Dysregulation of NR5A1 has been implicated in conditions such as adrenal insufficiency, gonadal dysgenesis, and reproductive disorders.
By targeting NR5A1 with this polyclonal antibody, researchers can accurately detect and analyze the protein in different cell types, paving the way for advancements in endocrinology and reproductive biology research.Overall, the NR5A1 Polyclonal Antibody (CAB1657) offers researchers a reliable tool for investigating the functions and mechanisms of NR5A1 in various physiological and pathological contexts, ultimately contributing to the development of novel therapies and treatment strategies for related disorders.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Steroidogenic factor-1 (SF-1/Steroidogenic factor-1 (SF-1/NR5A1)) (NP_004950.2).
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.
Purification Method:
Affinity purification
Gene ID:
2516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using Steroidogenic factor-1 (SF-1/NR5A1) Rabbit pAb (CAB1657) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
