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Steroidogenic factor-1 (SF-1/NR5A1) Rabbit Polyclonal Antibody (CAB1657)

SKU:
CAB1657
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

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Product Name:Steroidogenic factor-1 (SF-1/NR5A1) Rabbit Polyclonal Antibody
SKU:CAB1657
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Steroidogenic factor-1 (SF-1/Steroidogenic factor-1 (SF-1/NR5A1)) (NP_004950.2).
Sequence:MDYS YDED LDEL CPVC GDKV SGYH YGLL TCES CKGF FKRT VQNN KHYT CTES QSCK IDKT QRKR CPFC RFQK CLTV GMRL EAVR ADRM RGGR NKFG PMYK RDRA LKQQ KKAQ IRAN GFKL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:ELP; SF1; FTZ1; POF7; SF-1; AD4BP; FTZF1; SPGF8; SRXX4; SRXY3; hSF-1; Steroidogenic factor-1 (SF-1/NR5A1)
Positive Sample:HeLa,293T,Mouse testis
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:52kDa
Observed MW:50kDa

The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.

Purification Method:Affinity purification
Gene ID:2516
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse testis, using Steroidogenic factor-1 (SF-1/NR5A1) Rabbit pAb (CAB1657) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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