The NR4A2 Polyclonal Antibody (CAB17318) is a valuable tool for researchers studying NR4A2, a nuclear receptor involved in various physiological processes, including cell proliferation and differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot experiments.NR4A2, also known as Nurr1, is a transcription factor that regulates gene expression in the nervous system and is implicated in neurodegenerative diseases such as Parkinson's disease.
By targeting NR4A2 with this antibody, researchers can investigate its role in neuronal development, function, and pathology, offering insights into potential therapeutic strategies for neurological disorders.Overall, the NR4A2 Polyclonal Antibody (CAB17318) is a valuable tool for studies in neuroscience and neurology, providing researchers with the means to explore the functions and mechanisms of NR4A2 in health and disease.
Product Name:
NR4A2 Rabbit Polyclonal Antibody
SKU:
CAB17318
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-170 of human NR4A2 (NP_006177.1).
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
4929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB17318) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
