The NR2C2 Polyclonal Antibody (CAB6422) is a valuable tool for researchers studying NR2C2, a transcription factor that plays a crucial role in gene regulation and cell differentiation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is optimized for Western blot applications. By binding to the NR2C2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in developmental biology and cancer research.NR2C2, also known as nuclear receptor subfamily 2 group C member 2, is a key player in controlling gene expression and determining cellular fate.
Its involvement in regulating stem cell differentiation and tissue development highlights its importance in various physiological processes. Research into NR2C2 function is essential for understanding mechanisms of cell growth and differentiation, with potential implications for regenerative medicine and cancer therapy.By utilizing the NR2C2 Polyclonal Antibody (CAB6422), researchers can gain valuable insights into the role of NR2C2 in cellular processes and disease pathways, ultimately advancing our knowledge of gene regulation and potential therapeutic targets.
Product Name:
NR2C2 Rabbit Polyclonal Antibody
SKU:
CAB6422
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NR2C2 (NP_003289.2).
This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
7182
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of 293F, using NR2C2 Rabbit pAb (CAB6422) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
