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NR2C2 Rabbit Polyclonal Antibody (CAB6422)

SKU:
CAB6422
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NR2C2 Rabbit Polyclonal Antibody
SKU:CAB6422
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NR2C2 (NP_003289.2).
Sequence:LIAT PTFV ADKD GARQ TGLL DPGM LVNI QQPL IRED GTVL LATD SKAE TSQG ALGT LANV VTSL ANLS ESLN NGDT SEIQ PEDQ SASE ITRA FDTL AKAL NTTD SSSS PSLA DGID TSGG GSIH VISR DQST PIIE VEGP L
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:5000
Synonyms:TR4; TAK1; NR2C2
Positive Sample:293F
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:65kDa
Observed MW:67kDa

This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:7182
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of 293F, using NR2C2 Rabbit pAb (CAB6422) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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