The NQO2 Rabbit Monoclonal Antibody (CAB3846) is a valuable tool for researchers studying NQO2, an enzyme involved in redox reactions and antioxidant defense. This antibody, generated using rabbit monoclonal technology, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications.NQO2, also known as NAD(P)H dehydrogenase quinone 2, plays a crucial role in cellular responses to oxidative stress and detoxification processes. Its dysregulation has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
By targeting NQO2 with this antibody, researchers can investigate its expression levels and localization in different cell types, offering insights into its functions in health and disease.Overall, the NQO2 Rabbit Monoclonal Antibody (CAB3846) provides researchers with a valuable tool for studying the role of NQO2 in various biological processes, paving the way for new therapeutic strategies and approaches in the fields of oncology, neurobiology, and metabolism.
Product Name:
NQO2 Rabbit Monoclonal Antibody
SKU:
CAB3846
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NQO2 (P16083).
This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4835
Clone Number:
ARC0846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NQO2 Rabbit mAb (CAB3846) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.