The NQO2 Polyclonal Antibody (CAB5440) is a valuable tool for researchers studying NQO2, an enzyme involved in various cellular processes, including drug metabolism and antioxidant defense. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the NQO2 protein, this antibody allows for precise detection and analysis in a wide range of cell types, making it particularly useful for investigations in the fields of pharmacology and oxidative stress research.NQO2, also known as NAD(P)H dehydrogenase quinone 2, is a crucial enzyme in the cellular response to oxidative stress and plays a role in detoxification processes.
Dysregulation of NQO2 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions. By studying the function and expression of NQO2, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention. The NQO2 Polyclonal Antibody is a reliable tool for exploring the role of NQO2 in health and disease, paving the way for novel research discoveries and potential therapeutic advancements.
Product Name:
NQO2 Rabbit Polyclonal Antibody
SKU:
CAB5440
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-231 of human NQO2 (NP_000895.2).
This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4835
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using NQO2 antibody (CAB5440) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
