The NQO2 Polyclonal Antibody (CAB11742) is a valuable tool for researchers studying NQO2, a detoxifying enzyme involved in protecting cells from oxidative stress and carcinogens. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the NQO2 protein, this antibody allows for the accurate detection and analysis of NQO2 in a variety of cell types.NQO2 plays a crucial role in maintaining cellular function by reducing reactive oxygen species and detoxifying harmful compounds.
Its involvement in cellular defense mechanisms makes it an attractive target for research in fields such as cancer biology, neurodegenerative diseases, and drug metabolism. By studying the function of NQO2, researchers can gain insight into the mechanisms of cellular protection and develop novel therapeutic approaches for various diseases.
Product Name:
NQO2 Rabbit Polyclonal Antibody
SKU:
CAB11742
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-231 of human NQO2 (NP_000895.2).
This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4835
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NQO2 Rabbit pAb (CAB11742) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
