The NQO2 Polyclonal Antibody (PAC036434) is a valuable tool for researchers studying NQO2, a cytoplasmic enzyme involved in the regulation of cellular redox balance and response to oxidative stress. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By binding to the NQO2 protein, this antibody enables accurate detection and analysis in various cell types, serving as a key component in studies related to oxidative stress, cancer, and metabolic diseases.
NQO2 plays a crucial role in maintaining cellular health by detoxifying harmful quinones and preventing oxidative damage. Dysregulation of NQO2 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting the importance of exploring its function in different biological contexts. The NQO2 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of NQO2 in disease pathogenesis and potential therapeutic interventions.
Antibody Name:
Nqo2 Antibody (PACO36434)
Antibody SKU:
PACO36434
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Rat, Mouse
Immunogen:
Recombinant Rat Ribosyldihydronicotinamide dehydrogenase [quinone] protein (1-231AA)
Western blot. All lanes: Nqo2 antibody at 8µg/ml. Lane 1: Rat heart tissue. Lane 2: Mouse liver tissue. Lane 3: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 27 kDa. Observed band size: 27 kDa.
Background:
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
UniProt Protein Details:
NCBI Summary:
mouse homolog catalyzes the reduction of quinones and quinone derivatives; may protect against development of myelogenous hyperplasia , may contribute to menadione mediated hepatic toxicity [RGD, Feb 2006]
