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NQO2 Monoclonal Antibody [PAT1E3AT] (CPAB0103)

SKU:
CPAB0103
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT1E3AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

NQO2 Monoclonal Antibody [PAT1E3AT] (CPAB0103)

The NQO2 Polyclonal Antibody (CPAB0103) is a valuable tool for researchers studying NQO2, an enzyme involved in the regulation of cellular redox balance and detoxification processes. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the NQO2 protein, this antibody enables detection and analysis in various cell types, making it ideal for investigations in fields such as oxidative stress, cancer biology, and drug metabolism.

NQO2, also known as NAD(P)H:quinone oxidoreductase 2, plays a crucial role in protecting cells from oxidative damage and maintaining cellular health. Dysregulation of NQO2 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in cellular homeostasis. By understanding the function and regulation of NQO2, researchers can gain insights into potential therapeutic targets for conditions characterized by oxidative stress and metabolic dysfunction.

Product Name:NQO2 Antibody
Product Sku:CPAB0103
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NQO2 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NQO2 amino acids 1-231 purified from Ecoli.
Clone:PAT1E3AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:NQO2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:NQO2 is a flavoprotein that catalyzes the 2-electron reduction of diverse quinones, redox dyes, and the vitamin K menadione. NQO2 mainly uses dihydronicotinamide riboside (NRH) as the electron donor. NQO2 catalyzes the metabolic detoxification of quinones and their derivatives to hydroquinones. This detoxification process protects cells against quinone-induced oxidative stress, cytotoxicity and mutagenicity.
Synonyms:DHQV, DIA6, QR2, EC 1.10.99.2, NMOR2, NQO2, NRH:quinone oxidoreductase 2, NRH dehydrogenase [quinone] 2, Ribosyldihydronicotinamide dehydrogenase [quinone].
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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