NQO1 Rabbit Monoclonal Antibody (CAB19586)
- SKU:
- CAB19586
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NQO1 Rabbit Monoclonal Antibody |
SKU: | CAB19586 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NQO1 (P15559). |
Sequence: | MVGR RALI VLAH SERT SFNY AMKE AAAA ALKK KGWE VVES DLYA MNFN PIIS RKDI TGKL KDPA NFQY PAES VLAY KEGH LSPD IVAE QKKL EAAD LVIF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 IF/ICC,1:100 - 1:500 |
Synonyms: | DTD; QR1; DHQU; DIA4; NMOR1; NMORI; [KD Validated] NQO1 |
Positive Sample: | HeLa,Mouse Stomach,Rat Lung,Rat Stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 31kDa |
Observed MW: | 31kDa |
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 1728 |
Clone Number: | ARC56753 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |