The NPY6R Antibody (PAC050942) is a specific and sensitive tool for research involving the Neuropeptide Y Receptor Y6 (NPY6R), a G-protein coupled receptor involved in the regulation of feeding behavior and energy homeostasis. This polyclonal antibody is produced in rabbits and is optimized for detection of NPY6R in human samples, making it ideal for use in various research applications such as Western blotting.The NPY6R antibody binds specifically to the NPY6R protein, allowing for precise detection and analysis in different cell types and tissues. Its high reactivity and specificity make it a valuable tool for studying the role of NPY6R in various physiological and pathological processes, including obesity, diabetes, and metabolic disorders.
Given the importance of NPY6R in regulating energy balance and metabolic functions, research using this antibody can provide valuable insights into the molecular mechanisms underlying these conditions. By elucidating the function of NPY6R, researchers can potentially identify novel therapeutic targets for the treatment of metabolic disorders and related diseases.
Western Blot. Positive WB detected in: Mouse brain tissue, Rat brain tissue. All lanes: NPY6R antibody at 2.3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 34 kDa. Observed band size: 34 kDa..
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO50942 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO50942 at dilution of 1:100.
Background:
When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.
Synonyms:
Putative neuropeptide Y receptor type 6 (NPY6-R) (NPY Y1-like receptor) (Putative pancreatic polypeptide receptor 2) (PP2), NPY6R, NPY1RL Y2B
UniProt Protein Function:
NPY6R: When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 5q31.2Cellular Component: integral to plasma membraneMolecular Function: neuropeptide Y receptor activity; pancreatic polypeptide receptor activityBiological Process: blood circulation; cell surface receptor linked signal transduction; feeding behavior; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway
