The NPTX2 Polyclonal Antibody (CAB12031) is a valuable tool for researchers studying NPTX2, a protein implicated in synaptic plasticity and neurodevelopment. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting NPTX2 in human samples, making it ideal for use in Western blot applications.NPTX2, also known as neuronal pentraxin 2, is involved in mediating synaptic transmission and plasticity, playing a crucial role in cognitive function and memory formation. Dysregulation of NPTX2 has been linked to neurological disorders such as Alzheimer's disease and epilepsy, highlighting its importance in brain health and function.
By targeting NPTX2 with this polyclonal antibody, researchers can investigate the role of this protein in various cellular processes and pathological conditions, paving the way for new insights and potential therapeutic strategies in neurology and neuroscience. With its reliability and accuracy, the NPTX2 Polyclonal Antibody (CAB12031) is a valuable tool for advancing research in the field of neurobiology.
Product Name:
NPTX2 Rabbit Polyclonal Antibody
SKU:
CAB12031
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-240 of human NPTX2 (NP_002514.1).
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Purification Method:
Affinity purification
Gene ID:
4885
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NPTX2 Rabbit pAb (CAB12031) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
